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For 20 years, Flexcell International Corporation has specialized in designing and manufacturing products to service the Cytomechanics marketplace.
For 20 years, Flexcell® International Corporation has specialized in designing and manufacturing products to service the Cytomechanics marketplace. Cytomechanics is the field of study investigating cellular responses to mechanical loads. Flexcell® takes pride in the quality of our products and in the service we provide to our customers. We welcome you to our site to learn more about how you can expand your research capabilities.
Cells are subjected to compression, tension, and shear in the body and undergo specific biochemical changes to respond and adapt to deformation.
Stressing cells in culture simulates the in vivo environment causing dramatic morphologic and biochemical responses. There are both short and long term changes that occur when cells are loaded in culture, such as alterations in signaling, the rate and amount of protein synthesis, secretion, or degradation, the rate of cell division, changes in energy metabolism, and other changes in biochemistry and bioenergetics.
For these reasons, Flexcell® introduced tension, compression, and fluid shear systems for cell culturing. These systems have broad applications in the biomedical research field since strain, compression, or fluid flow have been found to induce biochemical changes in cells derived from a variety of tissues including cardiac, skeletal and smooth muscle, lung, vascular endothelium, skin, tendon, ligament, cartilage, and bone.
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